Opinion on Khat (katha edulis)?!
Question: What are the long term side effect? How is it used or taken? Where can I buy it?
Answer:
Chemistry/pharmacology
The stimulant effect of the plant was originally attributed to cathine, a phenethylamine-type substance isolated from the plant. However, the attribution was disputed by reports showing the plant extracts from fresh leaves contained another substance more behaviorally active than cathine. In 1975, the related alkaloid cathinone was isolated, and its absolute configuration was established in 1978. Cathinone is not very stable and breaks down to produce cathine and norephedrine. These chemicals belong to the PPA (phenylpropanolamine) family, a subset of the phenethylamines related to amphetamines and the catecholamines epinephrine and norepinephrine.
Khat consumption induces mild euphoria and excitement. Individuals become very talkative under the influence of the drug and may appear to be unrealistic and emotionally unstable. Khat can induce manic behaviors and hyperactivity. Several cases of khat-induced psychosis have been reported in the literature. Khat is an effective anorectic and its use also results in constipation. Dilated pupils (mydriasis), which are prominent during khat consumption, reflect the sympathomimetic effects of the drug, which are also reflected in increased heart rate and blood pressure. A state of drowsy hallucinations (hypnagogic hallucinations) may result coming down from khat use as well. Withdrawal symptoms that may follow prolonged khat use include lethargy, mild depression, nightmares, and slight tremor. Long term use can precipitate the following effects: negative impact on liver function, permanent tooth darkening (of a greenish tinge), susceptibility to ulcers, and diminished sex drive. Khat is usually not an addictive drug, although there are some people who cannot stay without it for more than 4-5 days. They feel tired and have difficulty concentrating.
The effects are not good as you can see from the extract of text above. Users chew the leaves of the plants. It is legal in the UK and is most widely used in the Somali and Yemeni community, so you would be likely to be able to buy it there....;
Answers: