How does SPECT using a gamma camera compare with PET and fMRI in measuring regional cerebral blood flow (rCBF)?!
Question: How does SPECT using a gamma camera compare with PET and fMRI in measuring regional cerebral blood flow (rCBF).?
Answers:
The main purpose of Single photon emission computed tomography (SPECT), when used in brain imaging, is to measure the regional cerebral blood flow (rCBF). The development of computed tomography in the 1970s allowed mapping of the distribution of the radioisotopes in the brain, and led to the technique now called SPECT.
The imaging agent used in SPECT emits gamma rays, as opposed to the positron emitters (such as 18F) used in positron emission tomography (PET). There are a range of radiotracers (such as 99mTc, 111In, 123I, 201Tl) that can be used, depending on the specific application.
Xenon (133Xe) gas is one such radiotracer. It has been shown to be valuable for diagnostic inhalation studies for the evaluation of pulmonary function; for imaging the lungs; and may also be used to assess rCBF. Detection of this gas occurs via a gamma camera
The imaging agent used in SPECT emits gamma rays, as opposed to the positron emitters (such as 18F) used in positron emission tomography (PET). There are a range of radiotracers (such as 99mTc, 111In, 123I, 201Tl) that can be used, depending on the specific application.
Xenon (133Xe) gas is one such radiotracer. It has been shown to be valuable for diagnostic inhalation studies for the evaluation of pulmonary function; for imaging the lungs; and may also be used to assess rCBF. Detection of this gas occurs via a gamma camera
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