what is neostigmine?!
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Neostigmine belongs to the group of medicines called anticholinesterases. It works by prolonging the action acetylcholine, which is found naturally in the body. It does this by inhibiting the action of the enzyme acetylcholinesterase. Acetylcholine stimulates a type of receptor called muscarinic receptors. When stimulated, these receptors have a range of effects.
Muscarinic receptors are found throughout the body, especially on muscle. Stimulation of these receptors causes to muscle contraction.
In myasthenia gravis the body's immune system destroys many of the muscarinic receptors, so that the muscle becomes less responsive to nervous stimulation. Neostigmine bromide increases the amount of acetylcholine at the nerve endings. Increased levels of acetyl choline allow the remaining receptors to function more efficiently. This medicine usually restores mucle function to near-normal levels.
What is it used for?
Abnormal muscle weakness (myasthenia gravis)
Difficulty in passing urine (urinary retention)
Failure of function of part of the gut causing an obstruction (paralytic ileus)
Use with caution in
Asthma
Decreased kidney function
Epilepsy
Low blood pressure (hypotension)
Parkinson's disease
People who have recently had a heart attack
Peptic ulcer
Slow heart rate of less than 50 beats per minute (bradycardia)
Not to be used in
Blockage of the gut (intestinal obstruction)
Known sensitivity or allergy to any ingredient
Obstruction of the urinary tract (urethra)
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http://health.yahoo.com
judging by the suffix i guess it's for migraine?
like: ergotamine
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