What does a muscle biopsy show?!


Question:
Answers:
A muscle biopsy may be performed for many reasons, including the following:
To distinguish between neurogenic (nerve) and myopathic (primarily muscle) disorders
To identify specific muscular disorders such as muscular dystrophy or congenital myopathy
To identify metabolic defects of the muscle
To diagnose diseases of the connective tissue and blood vessels (such as polyarteritis nodosa)
To diagnose infections that affect the muscles (such as trichinosis or toxoplasmosis)

Other Answers:
GENERAL INDICATIONS FOR MUSCLE BIOPSIES
Presence of some evidence of muscle disease are
1. Weakness
2. Muscle symptoms: Discomfort; Cramps; Fatigue with activity (r/o myasthenia)
3. Elevated (very high or high) creatine kinase (CK)
4. Myopathic EMG
5. Presence of a neuropathy for which a nerve biopsy is indicated
6. Presence of a systemic disorder that may have silent manifestations in muscle
7. Vasculitis
8. Sarcoidosis
9. Not generally indicated in some disorders better diagnosed by electrodiagnostic methods
10.Myasthenia gravis (May be suggested on biopsy if esterase-stained NMJs are small)
11.Myotonias
12.Wait: 1 month after episode of rhabdomyolysis
Source(s):
I am a Pharmacist
http://www.greencrossremedies.com

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