indocid dosage?!
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In chronic disorders, treatment should be started with a dosage of 25 mg 2 or 3 times a day. By starting therapy with low dosage, increased gradually when necessary, maximum benefit will be produced with fewer adverse reactions. Always give indomethacin with food or with antacids to reduce gastric irritation.
As with all drugs, the lowest possible effective dose should be utilized for each individual patient.
The drug should not be prescribed for children because safe conditions for use have not been established.
Since advancing years appear to increase the possibility of adverse reactions, indomethacin should be used with greater care in the elderly.
Adults: Rheumatoid arthritis and ankylosing (rheumatoid) spondylitis: Initial Dosage: 25 mg 2 or 3 times a day. If the response is not adequate, increase the daily dosage by 25 mg at about weekly intervals until a satisfactory response is obtained or a dosage of 150 to 200 mg/day is reached.
If a satisfactory response is not obtained with 200 mg a day, larger doses probably will not be effective.
If adverse reactions develop as the dosage is increased, reduce the dosage to a tolerated level and maintain this for 3 to 4 weeks. If an adequate response has not been obtained, gradually increase the daily dosage by 25 mg at about weekly intervals to 150 mg to 200 mg a day.
For patients with acute rheumatoid arthritis or with acute flares of chronic rheumatoid arthritis, increase the dosage daily by 25 mg until a satisfactory response is obtained or a total daily dosage of 150 to 200 mg is reached. If adverse effects develop as the dosage is increased, the dosage should be reduced to a tolerated level for 2 or 3 days, and then gradually increased by 25 mg every few days as tolerated. After the acute phase is under control, it is often possible to reduce the daily dosage gradually to 75 to 100 mg.
Reduction of Steroid Dosage: Use of indomethacin often will permit a gradual reduction of steroid dosage by 25 to 50%. In some patients steroids can be slowly discontinued over a period of several weeks or months. The usual precautions should be observed in withdrawing steroids.
Severe Osteoarthritis and Degenerative Joint Disease of the Hip: Initial Dosage: 25 mg 2 or 3 times a day. If the response is not adequate, increase the daily dosage by 25 mg at about weekly intervals until a satisfactory response is obtained or a dosage of 150 to 200 mg a day is reached. If a satisfactory response is not obtained with 200 mg/day, larger doses will probably not be effective.
If adverse reactions develop as the dosage is increased, reduce the dosage to a tolerated level and maintain this for 3 to 4 weeks. If an adequate response has not then been obtained, gradually increase the daily dosage by 25 mg at about weekly intervals to 150 to 200 mg a day.
Gout: To Control Acute Attacks: 50 mg 3 times a day until all signs and symptoms subside. Definite relief of pain has been reported within 2 to 4 hours. Tenderness and heat usually subside in 24 to 36 hours, and swelling gradually disappears in 3 to 5 days.
Indocid SR capsules are not recommended for use in acute attacks of gout.
Use of Alternate Dosage Forms: Indocid SR: Indocid SR may be tried after the daily dose has been established using the standard capsules and found to fall within 75 to 150 mg range. Patients stabilized on 25 mg three times daily should be tried on 1 SR capsule once daily and those stabilized on 50 mg 3 times daily should be tried on one SR capsule twice daily.
Indocid Suppositories: The recommended dosage is 100 to 200 mg daily and should be individually adjusted to the patient's response and tolerance. Daily dose of 100 mg can be given as 50 mg twice daily or as 100 mg at night. Doses higher than 100 mg must be given on a twice daily schedule.
Combined Administration: One 50 mg or 100 mg suppository at bedtime, supplemented the following day by 25 mg capsules as needed up to a total of 150 to 200 mg of indomethacin. The total daily dose of Indocid (capsules and suppositories) should not exceed 200 mg.
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shouldn't you ask a professional Doctor in the medical field ,I think so
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