whatdisease is from purple urine?!
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Purple urine bag syndrome (PUBS) is a rare syndrome associated with alkaline urine and some urinary tract infections, and is more frequently observed in chronically catheterized and constipated women. The urinary catheter drainage system changes colour from red or blue to violet or purple, sometimes with differently coloured tube and bag. The aetiology is still controversial but in the literature researched most authors believe that indigo, which is blue, and indirubin, which is red, are responsible for the colours obtained.
The chain reaction responsible for the PUBS begins with tryptophan from the food chain being metabolized by gut bacteria. This metabolic process produces indole, which is absorbed into portal circulation and converted into indoxyl sulphate in the liver, after a series of detoxification transformations.
Indoxyl sulphate is excessively excreted in the urine and is digested into indoxyl by the enzyme sulphatase/phosphatase produced by certain bacteria such as Pseudomonas aeruginosa, Proteus mirabilis, Morganella morganii, Escherichia coli, and so on. Indoxyl then changes into indigo and indirubin in alkaline urine [1,2].
Concerning PUBS, we present the clinical case report of a 56-year-old female patient with amyotrophic lateral sclerosis, mechanically ventilated in the intensive care unit for almost 6 years, chronically catheterized and with alkaline urine. Isolation of the bacteria M. morganii, P. aeruginosa and P. mirabilis in urine culture was frequent. The urinary catheter drainage system and the bag varied in colour and increased in intensity the longer the system remained unchanged (Figs 1, 2, 3 show different discolourations).
Considering the known etiologic and physiopathologic mechanisms of PUBS, it is surprising how rarely this situation is observed and/or reported.
Other Answers:
what have you been eating or drinking,is more like it
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nurse
Purple Grape Juice
There is no purple urine. Either Red brown or dark brown to black or certain other colours. Red brown is due to Urates, porphyria, or myoglobinuria. P Dark brown to black color is due to Alkaptonuria, melanosis or tyrinosis.
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