what are two conditions affecting the peripheral nervous system?!
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Generally, multiple sclerosis and neurofibromatosis. The former is a demyelinating disease of unknown origin that can strike at any age, but tends to afflict those of middle age (40s or 50s). The latter is a genetic condition where neurofibromas--benign tumors--form on the peripheral nerves.
These conditions may also affect the CNS, but are known most prominently for their peripheral effects.
Other Answers:
axonal degeneration (Wallerian degeneration, dying back) or demyelinating degeneration. Some overlap is common.
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